Being a native Windows user, I really dislike the layout of the keyboard on the MacBooks. In particular, I dislike the lack of delete, home, end, page up, and page down keys. While all of these can still be achieved using key combinations, I would still prefer to hit just one key. Another annoyance is that Mac OS X uses the command key for almost all the same shortcuts that Windows uses the control key. Since I dual boot my MacBook and use both operating systems regularly, my fingers tend to move faster than my brain and hit the wrong key all the time.
Fortunately, there are a couple of tools that have made my life a bit easier. DoubleCommand and SharpKeys are key remapping utilities for Mac OS X and Windows, respectively. They allow you to customize the layout of the keyboard and switch keys around using software. Using them collaboratively, I successfully switched the control and command keys in Windows and mapped the right alt/option/enter key to the delete key. It does not solve all of the annoyances, but now I do have a delete key and do not have to worry about different key combinations for copy and paste in the different operating systems.
Now, if only Apple had two mouse buttons on the MacBook instead of one…
